nitric oxide synthases — TargetMol Chemicals

Cat No.	Product Name	Synonyms	Targets
TQ0301	Kuwanon A		NO Synthase
	Kuwanon A inhibits nitric oxide production (IC50: 10.5 μM). Kuwanon A is a flavone derivative isolated from Morus alba L.		NO Synthase
T6S2023	Harpagoside		Others , COX , NO Synthase
	1. Harpagoside has anti-inflammatory activity. 2. Harpagoside at 3 mM concentration, shows moderate inhibition of seed germination. 3. Harpagoside can inhibit lipopolysaccharide-induced mRNA levels and protein expression...		Others , COX , NO Synthase
T6S1665	Irisflorentin		Others , NO Synthase
	1. Irisflorentin blocks apoptosis pathways, by exerting its effects by promoting rpn-3 expression to enhance the activity of proteasomes and down-regulating egl-1 expression. 2. Irisflorentin has anti-inflammatory mechan...		Others , NO Synthase
T2S0765	Epibetulinic acid		NO Synthase , Prostaglandin Receptor
	Epibetulinic acid has anti-inflammatory activity, it exhibits potent inhibitory effects on NO and prostaglandin E(2) production in mouse macrophages (RAW 264.7) stimulated with bacterial endotoxin.		NO Synthase , Prostaglandin Receptor
T7682	Asymmetric dimethylarginine		Endogenous Metabolite , NO Synthase , NOD
	Asymmetric dimethylarginine is an endogenous inhibitor of nitric oxide synthase (NOS)		Endogenous Metabolite , NO Synthase , NOD
T7474	7-Nitroindazole		NOS
	7-Nitroindazole is a non-selective inhibitor of NOS isoforms in vitro for neuronal nitric oxide synthase showing a 10-fold selectivity for neuronal NOS.		NOS
T10107	3-Bromo-7-nitroindazole		NOS
	3-Bromo-7-nitroindazole is a more potent and selective inhibitor of neuronal nitric oxide synthase (nNOS) than eNOS or iNOS. It affects the intercellular messenger NO synthesis throughout the brain and body.		NOS
T3847	Asperuloside	Asperulosid	Others , NO Synthase
	Asperuloside (Asperulosid) has anti-inflammatory activity.		Others , NO Synthase
T5838	L-Canavanine sulfate		NO Synthase , NOD
	L-Canavanine sulfate is a selective inducible NO synthase inhibitor.		NO Synthase , NOD
T1322	Bendazol	Dibazol,Dibazole	Dopamine Receptor , NO Synthase
	Bendazol (Dibazol) is always used as the drug for hypertension and cerebral Angiospasm.		Dopamine Receptor , NO Synthase
T5S0285	Cistanoside A		Others
	1. Cistanoside A possesses protective activities on CCl4 induced hepatotoxicity in mice, which is involved with increasing free radicals clearing activities, alleviating lipid-overoxidation damage, and improving respirat...		Others
T22724	Dimaprit dihydrochloride		NOS , NO Synthase , Histamine Receptor
	Dimaprit dihydrochloride is a selective histamine H2 receptor agonist. Dimaprit dihydrochloride also inhibits nNOS with an IC50 of 49 μM. It can stimulate gastric acid secretion.		NOS , NO Synthase , Histamine Receptor
T2791	Pectolinarin		Apoptosis , Others , NO Synthase , Prostaglandin Receptor , Interleukin
	Pectolinarin is a Cirsium isolate with anti-inflammatory activity.
T7597	6-Biopterin	L-Biopterin	Endogenous Metabolite , NO Synthase , NOD
	6-Biopterin (L-Biopterin) is a natural product,is a NO synthase cofactor.		Endogenous Metabolite , NO Synthase , NOD
T4808	Agmatine sulfate	Agmatine sulfate salt	Endogenous Metabolite , NO Synthase , Imidazoline Receptor
	Agmatine sulfate (Agmatine sulfate salt) is a bioactive metabolite of the arginine amino acid. It exerts modulatory action at multiple molecular targets, such as neurotransmitter systems, ion channels and nitric oxide sy...		Endogenous Metabolite , NO Synthase , Imidazoline Receptor
TN2139	Regaloside B		NOS , COX , NO Synthase
	Regaloside B, a phenylpropanoid isolated from Lilium longiflorum, exhibits anti-inflammatory activity by inhibiting the expression of iNOS (inducible nitric oxide synthase) and COX-2 (cyclooxygenase-2).		NOS , COX , NO Synthase
T2980	Chondroitin sulfate	Chonsurid,Chondroitin polysulfate	MMP , Others , Endogenous Metabolite , NO Synthase
	Chondroitin sulfate (Chonsurid) is extracted from shark bone;Store the product in sealed, cool and dry condition		MMP , Others , Endogenous Metabolite , NO Synthase
T19853	Dimethoxycurcumin	Veratrylcurcuminoid	Others
	Dimethoxycurcumin (Veratrylcurcuminoid) is an analog of curcumin with more metabolical stability. Dimethoxycurcumin induces epigenetic changes in leukemia cells and the expression of promoter methylated genes.		Others
T2S2335	Dehydroevodiamine	DHED	Others , NF-κB , COX , PGE Synthase , NO Synthase
	Dehydroevodiamine (DHED), a constituent of Evodia rutaecarpa, has various biological effects such as hypotensive, negative chronotropic, ion channel depressant, inhibition of nitric oxide production and cerebral blood fl...		Others , NF-κB , COX , PGE Synthase , NO Synthase
T15697	L-NMMA acetate	Tilarginine acetate,Methylarginine acetate	NOS
	L-NMMA acetate (Tilarginine acetate) is an inhibitor of nitric oxide synthase of all NOS isoforms (i.e. NOS1, NOS2, and NOS3). The Ki values are 0.18, 0.4, and 6 µM for nNOS, eNOS, and iNOS, respectively.		NOS